MS-ISAC: Defending America’s Critical Infrastructure

The Multi-State Information Sharing and Analysis Center (MS-ISAC) provides vital cybersecurity services to more than 18,000 state, local, tribal, and territorial (SLTT) government organizations supporting our nation’s critical infrastructure including public hospitals, public utilities, K-12 schools, and law enforcement. Without these services, they will be increasingly vulnerable to cyber attacks by foreign adversaries.

The MS-ISAC is the only initiative offering cyber threat intelligence, incident response support, and real-time information sharing programs not performed by the federal government.

Defense Against Costly Cyber Threats

As threats against state and local governments grow in volume and complexity, the average cost of a cyber attack for state and local governments can range from $2.83 million to $9.5 million, with some reports indicating even higher costs, depending on the type and severity of the breach.

In 2024, the MS-ISAC took the defensive measures below in an effort to protect SLTTs across the U.S.

Detected 40,000+ potential cyber attacks targeting SLTT networks

Impacted MS-ISAC members received alert notifications nearly twice as fast as commercially-available alternatives.

Detected and prevented 59,000+ malware and ransomware attacks

MS-ISAC members were supported with endpoint protection services that identify, detect, respond to, and remediate security incidents and alerts.

Blocked 25,000,000,000+ malicious domain connections for SLTTs

The MS-ISAC's protective DNS service blocked an average of 3.3M requests to known or suspected malicious domains per member organization.

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Current Member benefits expired October 1, 2025
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