A Vulnerability in Cisco AsyncOS Could Allow for Remote Code Execution

MS-ISAC ADVISORY NUMBER:

2025-117

DATE(S) ISSUED:

12/18/2025

OVERVIEW:

A vulnerability has been discovered in Cisco AsyncOS, which could allow for remote code execution. AsyncOS is the operating system used by Cisco Secure Email Gateway and Cisco Secure Email and Web Manager. Successful exploitation of this vulnerability could allow an attacker to execute arbitrary commands with root-level privileges on the underlying operating system.

THREAT INTELLIGENCE:

Cisco confirmed active exploitation of a previously unknown, maximum-severity vulnerability affecting Cisco Secure Email Gateway and Cisco Secure Email and Web Manager appliances running AsyncOS. The flaw, tracked as CVE-2025-20393, is already being abused in real-world attacks and allows threat actors to gain deep control over affected systems. 

The U.S. Cybersecurity and Infrastructure Security Agency (CISA) added CVE-2025-20393 to its Known Exploited Vulnerabilities (KEV) catalog.

SYSTEMS AFFECTED:

  • All releases of Cisco AsyncOS Software are affected when both of the following conditions are met:
  • - The appliance is configured with the Spam Quarantine feature.
  • - The Spam Quarantine feature is exposed to and reachable from the internet.
  • - The Spam Quarantine feature is not enabled by default. Deployment guides for these products do not require this port to be directly exposed to the Internet.

RISK:

Government:
Large and medium government entitiesHIGH
Small governmentMEDIUM
Businesses:
Large and medium business entitiesHIGH
Small business entitiesMEDIUM
Home Users:
LOW

TECHNICAL SUMMARY:

A vulnerability has been discovered Cisco AsyncOS, which could allow for remote code execution. Details of the vulnerability is as follows: 

Tactic: Initial Access (TA0001):

Technique: Exploit Public-Facing Application (T1190):

  • According to the Cisco Security Advisory, Cisco became aware of a new cyberattack campaign targeting a limited subset of appliances with certain ports open to the internet that are running Cisco AsyncOS Software for Cisco Secure Email Gateway and Cisco Secure Email and Web Manager on December 10. This attack allows the threat actors to execute arbitrary commands with root privileges on the underlying operating system of an affected appliance. The ongoing investigation has revealed evidence of a persistence mechanism planted by the threat actors to maintain a degree of control over compromised appliances. (CVE-2025-20393)
  • No patch is available at the time of this advisory. Cisco recommends the following mitigations:
  • If an appliance has been identified as having the web management interface or the Spam Quarantine port exposed to and reachable from the internet, Cisco strongly recommends to restore the appliance to a secure configuration, when possible.
  • If restoring the appliance is not possible, Cisco recommends contacting TAC to check whether the appliance has been compromised. In case of confirmed compromise, rebuilding the appliances is, currently, the only viable option to eradicate the threat actors persistence mechanism from the appliance.
  • Cisco strongly recommends restricting access to the appliance and implementing robust access control mechanisms to ensure that ports are not exposed to unsecured networks.

Successful exploitation of this vulnerability could allow an attacker to execute arbitrary commands with root-level privileges on the underlying operating system.

RECOMMENDATIONS:

We recommend the following actions be taken: 

* Once available, apply appropriate workarounds provided by Cisco to vulnerable systems immediately after appropriate testing. (M1051: Update Software) 

o Safeguard 7.1 : Establish and Maintain a Vulnerability Management Process: Establish and maintain a documented vulnerability management process for enterprise assets. Review and update documentation annually, or when significant enterprise changes occur that could impact this Safeguard.

o Safeguard 7.2: Establish and Maintain a Remediation Process: Establish and maintain a risk-based remediation strategy documented in a remediation process, with monthly, or more frequent, reviews.

o Safeguard 7.4: Perform Automated Application Patch Management: Perform application updates on enterprise assets through automated patch management on a monthly, or more frequent, basis.

o Safeguard 7.5 : Perform Automated Vulnerability Scans of Internal Enterprise Assets: Perform automated vulnerability scans of internal enterprise assets on a quarterly, or more frequent, basis. Conduct both authenticated and unauthenticated scans, using a SCAP-compliant vulnerability scanning tool.

o Safeguard 7.7: Remediate Detected Vulnerabilities: Remediate detected vulnerabilities in software through processes and tooling on a monthly, or more frequent, basis, based on the remediation process.

o Safeguard 12.1: Ensure Network Infrastructure is Up-to-Date: Ensure network infrastructure is kept up-to-date. Example implementations include running the latest stable release of software and/or using currently supported network-as-a-service (NaaS) offerings. Review software versions monthly, or more frequently, to verify software support.

o Safeguard 18.1: Establish and Maintain a Penetration Testing Program: Establish and maintain a penetration testing program appropriate to the size, complexity, and maturity of the enterprise. Penetration testing program characteristics include scope, such as network, web application, Application Programming Interface (API), hosted services, and physical premise controls; frequency; limitations, such as acceptable hours, and excluded attack types; point of contact information; remediation, such as how findings will be routed internally; and retrospective requirements.

o Safeguard 18.2: Perform Periodic External Penetration Tests: Perform periodic external penetration tests based on program requirements, no less than annually. External penetration testing must include enterprise and environmental reconnaissance to detect exploitable information. Penetration testing requires specialized skills and experience and must be conducted through a qualified party. The testing may be clear box or opaque box.

o Safeguard 18.3: Remediate Penetration Test Findings: Remediate penetration test findings based on the enterprise’s policy for remediation scope and prioritization.

* Apply the Principle of Least Privilege to all systems and services. Run all software as a non-privileged user (one without administrative privileges) to diminish the effects of a successful attack. (M1026: Privileged Account Management) 

o Safeguard 4.7: Manage Default Accounts on Enterprise Assets and Software: Manage default accounts on enterprise assets and software, such as root, administrator, and other pre-configured vendor accounts. Example implementations can include: disabling default accounts or making them unusable.

o Safeguard 5.5: Establish and Maintain an Inventory of Service Accounts: Establish and maintain an inventory of service accounts. The inventory, at a minimum, must contain department owner, review date, and purpose. Perform service account reviews to validate that all active accounts are authorized, on a recurring schedule at a minimum quarterly, or more frequently.

* Vulnerability scanning is used to find potentially exploitable software vulnerabilities to remediate them. (M1016: Vulnerability Scanning) 

o Safeguard 16.13: Conduct Application Penetration Testing: Conduct application penetration testing. For critical applications, authenticated penetration testing is better suited to finding business logic vulnerabilities than code scanning and automated security testing. Penetration testing relies on the skill of the tester to manually manipulate an application as an authenticated and unauthenticated user.

* Architect sections of the network to isolate critical systems, functions, or resources. Use physical and logical segmentation to prevent access to potentially sensitive systems and information. Use a DMZ to contain any internet-facing services that should not be exposed from the internal network. Configure separate virtual private cloud (VPC) instances to isolate critical cloud systems. (M1030: Network Segmentation) 

o Safeguard 12.2: Establish and Maintain a Secure Network Architecture: Establish and maintain a secure network architecture. A secure network architecture must address segmentation, least privilege, and availability, at a minimum.

* Use capabilities to detect and block conditions that may lead to or be indicative of a software exploit occurring. (M1050: Exploit Protection) 

o Safeguard 10.5: Enable Anti-Exploitation Features: Enable anti-exploitation features on enterprise assets and software, where possible, such as Microsoft® Data Execution Prevention (DEP), Windows® Defender Exploit Guard (WDEG), or Apple® System Integrity Protection (SIP) and Gatekeeper™.


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